0112-1159 Sommer
Sommer B, Sattler G.
Current concepts of fat graft survival: histology of aspirated adipose tissue
and review of the literature. Dermatol Surg. 2000 Dec;26(12):1159-66. PMID: 11134994
Rosenparkklinik Darmstadt, Cosmetic Dermatologic Surgery, Darmstadt, Germany.
BACKGROUND: Controversy remains about the longevity of correction in autologous
fat grafts and its relation to adipocyte survival. Reported long-term fat graft
survival rates differ widely, depending on harvesting method, means of
reinjection, injection site, and evaluation methods. OBJECTIVE: To demonstrate
histologic findings of aspirated adipose tissue and compare the findings to the
reports in the literature. METHODS: Review of the literature and the histology
of transplanted fat 7 years after subcutaneous implantation and trypan blue
staining to determine the vitality of defrosted adipocytes. RESULTS: Fat cells
survive aspiration with a suction machine or syringe equally well. Use of a
liposuction cannula or 14-gauge needle gives comparable results. Local
anesthesia or tumescent local anesthesia is recommended for the donor site,
preferably with addition of epinephrine. CONCLUSION: Clinical longevity of
correction after autologous fat transfer is determined by the degree of
augmentation resulting from the amount of fibrosis induced and the number of
viable fat cells. Survival of aspirated fat cell grafts depends mainly on the
anatomic site, the mobility and vascularity of the recipient tissue, or
underlying causes and diseases, and less on harvesting and reinjection methods.
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