| 0211-979 James
James J, Carruthers A, Carruthers J.
HIV-associated facial lipoatrophy. Dermatol Surg. 2002 Nov;28(11):979-86. PMID: 12460289
Division of Dermatology and Department of Ophthalmology, University of British
Columbia, Vancouver,British Columbia, Canada.
BACKGROUND: HIV-infected individuals are living long, healthy lives. They are
now concerned with less life-threatening problems, especially lipodystrophy.
OBJECTIVE: To review the current state of our knowledge about lipodystrophy in
HIV-infected individuals. METHODS: The literature was reviewed and analyzed for
relevant information. In addition, our clinical experience of managing such
individuals was utilized. RESULTS: Lipodystrophy and facial lipoatrophy and
their relationship to HIV-infection are discussed. Their differences are noted.
The spectrum of appearance in individuals with facial lipoatrophy is described
and a severity scale suggested which should be of value in assessing the results
of treatment. CONCLUSION: Lipodystrophy and lipoatrophy are intimately related
to infection with HIV. In consequence, facial lipoatrophy is a major stigma for
HIV-infected individuals and can have dramatic effects on their self-esteem and
socialization. Effective treatment is essential.
Publication Types:
Review
Review, Tutorial
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