| 0211-1022 Proebstle
Proebstle TM, Schneiders V, Knop J.
Gravimetrically controlled efficacy of subcorial curettage: a prospective study
for treatment of axillary hyperhidrosis. Dermatol Surg. 2002 Nov;28(11):1022-6. PMID: 12460297
Department of Dermatology, University of Mainz, Mainz, Germany.
Thomas.Proebstle@web.de
BACKGROUND: Botulinum toxin A (BTX-A) proved to be effective for the treatment
of axillary hyperhidrosis by means of gravimetry. Quantitatively controlled
studies for surgical treatment are lacking so far. OBJECTIVE: To prospectively
test the efficacy of subcorial axillary curettage by gravimetric evaluation of
pre- and postsurgical sweat rates. METHODS: Conservatively pretreated patients
received subcorial curettage under tumescent local anesthesia using a sharp
spoon. Sweat rates of each axilla were determined gravimetrically before and 4-8
weeks after surgery. Evaluation was performed with respect to baseline sweat
rates greater than 50 mg/min (group A), greater than 25 and less than 50 mg/min
(group B), and less than 25 mg/min (group C). Side effects and patients' ratings
were also recorded. RESULTS: Of 42 treated patients, 38 could be evaluated
completely. In 29 axillae of group A (high sweat rates), an average reduction
from the baseline of 85.6 mg/min to 21.6 mg/min could be achieved (P <.0001).
Corresponding values for 22 axillae of group B (medium sweat rates) were 36.8
mg/min and 16.5 mg/min (P <.0001). In 25 axillae with low sweat rates (group C),
a significant reduction in sweat rates could not be achieved. The results
remained almost stable during a median follow-up of 11 months (range 4-24
months). Only minor side effects were observed and patient satisfaction was high
in groups A and B. CONCLUSION: Subcorial curettage is an effective treatment of
axillary hyperhidrosis for patients with baseline sweat rates greater than 25
mg/min.
Publication Types:
Evaluation Studies
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