9311-1085 Klein
Klein JA.
Tumescent technique for local anesthesia improves safety in large-volume liposuction. Plast Reconstr Surg. 1993 Nov;92(6):1085-98; discussion 1099-100. PMID: 8234507
Comment in:
Plast Reconstr Surg. 1994 Dec;94(7):1096-7.
Plast Reconstr Surg. 1994 Jul;94(1):216.
Plast Reconstr Surg. 1994 Jul;94(1):216-7.
Plast Reconstr Surg. 1995 Mar;95(3):603-5.
Department of Dermatology, University of California, Irvine.
The tumescent technique for local anesthesia improves the safety of large-volume
liposuction ( > or = 1500 ml of fat) by virtually eliminating surgical blood
loss and by completely eliminating the risks of general anesthesia. Results of
two prospective studies of large-volume liposuction using the tumescent
technique are reported. In 112 patients, the mean lidocaine dosage was 33.3
mg/kg, the mean volume of aspirated material was 2657 ml, and the mean volume of
supernatant fat was 1945 ml. The mean volume of whole blood aspirated by
liposuction was 18.5 ml. For each 1000 ml of fat removed, 9.7 ml of whole blood
was suctioned. In 31 large-volume liposuction patients treated in 1991, the mean
difference between preoperative and 1-week postoperative hematocrits was -1.9
percent. The last 87 patients received no parenteral sedation. In a second
study, a 75-kg woman received 35 mg/kg of lidocaine on two separate occasions,
first without liposuction and 25 days later with liposuction; peak plasma
lidocaine concentrations occurred at 14 and 11 hours after beginning the
infiltration and were 2.37 and 1.86 micrograms/ml, respectively.
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