9409-496 Niechajev
Niechajev I, Sevcuk O.
Long-term results of fat transplantation: clinical and histologic studies.
Plast Reconstr Surg. 1994 Sep;94(3):496-506. PMID: 8047602
Comment in:
Plast Reconstr Surg. 1995 Apr;95(5):933.
Lidingo-kliniken, Karolinska Institutet, Stockholm, Sweden.
Nine cases of idiopathic constitutional subcutaneous fat atrophy in the cheek
area during the years 1988-1992 were treated by the autologous transplantation
of fat for purely aesthetic reasons. The fat graft suspension was obtained by
the low-power aspiration technique with the use of a vacuum pump. The contour
defects were initially overcorrected by approximately 50 percent more volume
than required. The patients were followed up for 1.5 to 4.5 (mean, 3.5) years.
Contrary to the experience of others, only the partial resorption of the
transplanted fat occurred. This result was verified by six biopsy specimens
obtained in the time range of 7 to 36 months after transplantation. The
additional injections of fat were not necessary. Delicate tissue handling and
the small total amount of fat transplanted by careful distribution in the
recipient tissues are probably the factors responsible for the long-lasting
improvement in these patients. As an experiment, suction of fat under -0.5 atm
and -0.95 atm was performed in five patients undergoing abdominal liposuction.
Aspiration under maximum negative pressure caused partial breakage and
vaporization of the fatty tissue. The diameter of the fat cells in the remaining
beads of fat was in all five cases mechanically distended and thus was larger
than in the lipocytes extracted at -0.5 atm.
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