9911-1823 Gruber
Gruber RP, Morley B.
Ketamine-assisted intravenous sedation with midazolam: benefits and potential
problems.
Plast Reconstr Surg. 1999 Nov;104(6):1823-5; discussion 1826-7.
PMID: 10541187
Stanford University, Oakland, Calif, USA. rgruber@pacbell.net
A review of 134 cases of ketamine-induced intravenous sedation was undertaken.
It was concluded that (1) whereas properly titrated midazolam with low-dose
ketamine (0.5 mg/kg) can provide almost complete absence of behavioral problems
and complete analgesia, transient oxygen desaturation may be seen, and (2) the
induction phase of ketamine is an opportunity for the surgeon to rehearse mask
ventilation.
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