| PRS 0401-391-Rohrich
Rohrich RJ, Sorokin ES, Brown SA.
In search of improved fat transfer viability: a quantitative analysis of the
role of centrifugation and harvest site.
Plast Reconstr Surg. 2004 Jan;113(1):391-5; discussion 396-7. PMID: 14707664
Department of Plastic Surgery, University of Texas Southwestern Medical Center,
Dallas 75390-9132, USA. rod.rohrich@utsouthwestern.edu
Fat grafting is an unpredictable procedure that continues to challenge the field
of plastic surgery due to irregular resorption. Applications for this procedure
are broad in both reconstructive and cosmetic plastic surgery. Fat grafts are
carefully obtained and manipulated to obtain better graft takes and results, yet
there is no universal agreement on what constitutes an ideal methodology. The
present study examines adipocyte viability from four commonly used donor sites
in five subjects. No statistical differences in adipocyte viability were
demonstrated among abdominal fat, thigh fat, flank fat, or knee fat donor sites
that were immediately removed and untreated (p < 0.225). In addition, no
differences were observed in representative tissue samples that were removed and
centrifuged (thigh, p = 0.508; knee, p = 0.302; flank, p = 0.088; abdomen, p =
0.533). On the basis of these quantitative data, neither harvest location nor
centrifugation demonstrated any advantage in terms of lipocyte viability. Fat
tissue transfers from these common sites may be considered equal, and
centrifugation does not appear to enhance immediate fat tissue viability before
implantation.
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